Protein Purification
MilliporeSigma™ Calbiochem™ α2-Antiplasmin, Human Plasma
A 452-amino acid glycoprotein present in plasma at about 70 μg/ml.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G.
MilliporeSigma™ Calbiochem™ (±)-Blebbistatin
(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.
MilliporeSigma™ Calbiochem™ CA-074 Me
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
MilliporeSigma™ Calbiochem™ Calpain Substrate III, Fluorogenic
A fluorogenic FRET peptide with a substrate sequence that is optimized for calpain-1 and -2.
MilliporeSigma™ Calbiochem™ ALLN
ALLN, CAS 110044-82-1, is a cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM).
MilliporeSigma™ Calbiochem™ Calyculin A, Discodermia calyx
Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC50 = 0.5-1 nM) and protein phosphatase 1 (PP1; IC50 = 2 nM).
MilliporeSigma™ Calbiochem™ PRIMA-1
A cell-permeable quinuclidinone analog with antitumor properties.
MilliporeSigma™ Calbiochem™ Val-boroPro
An orally available amino boronic acid dipeptide with antihyperglycemic and anticancer properties
MilliporeSigma™ Calbiochem™ PI 3-Kα Inhibitor VIII
The PI 3-Kα Inhibitor VIII controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ STING Agonist, 2ʹ3ʹ-cGAMP
A cyclic-dinucleotide (cyclic-GMP-AMP) based compound that binds to the C-terminal domain of adaptor endoplasmic reticulum protein known as STING with high affinity (Kd = 4nM) and induces the synthesis of interferon-b (IFN-b) in mammalian cells (EC50 =
MilliporeSigma™ Calbiochem™ PKR Inhibitor, Negative Control
The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Piceatannol
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3μM), PKC (IC50 = 8μM), MLCK (IC50 = 12μM).
MilliporeSigma™ Calbiochem™ Prodigiosin Serratia marcescens
A cell-permeable tripyrrole alkaloid compound that displays immunosuppressive and anti-tumor properties irrespective of p53 status and multidrug resistance.